Brain Protection and
Prevention of Brain Degeneration

Brain Protection and Prevention of Brain Degeneration

An in vitro study on Caviarlieri which is published in a peer reviewed journal proved that Caviarlieri facilitates the differentiation of the whole set of brain cells (neurons, astrocytes and oligodendrocytes). The observed reciprocal response between neuronal and glial populations suggests that Caviarlieri  can potentially affect a neuronal lineage of the neural progenitor cells. Thus, Caviarlieri can effectively protect degeneration in some integral parts of the brain, specifically the Hippocampus and may be able to stimulate neurogenesis in the mature brain.

Effective properties of a sturgeon-based bioactive compound on stress-induced hippocampal degeneration and on in vitro neurogenesis




F Marotta, DH Chui, H Yadav, A Lorenzetti, Celep G, S Jain, A Bomba, A Polimeni, K Zhong, F Allegri

Journal of Biological Regulators & Homeostatic Agents
Volume 26 Number 3, July-September 2012

Objective




The aim of this study was to test the activity of a marine bioactive compound containing high-purity caviar-derived DNA, collagen elastin and protein extracts from sturgeon to exert neuroprotective properties in an experimental setting while also being potential triggers of neurogenesis in a separate in vitro study. Supplementation with high-DHA mixture and Caviar DNA Extract (LD-1227) in Caviarlieri was applied for 30 days to stress model muriels. Both supplementations significantly mitigated the histological brain damage when analysing hippocampal subregions and corticosterone level. However, Caviar DNA Extract (LD-1227) was most significantly efficient in preventing SOD, Catalase and ascorbic acid decrease in brain tissue as compared to DHA.

Positive Effect of Caviarlieri on Brain Degeneration Cells

Method:

Muriels were subjected to immobilization stress and given orally (or mixed in their regular diet) as follows:

Group A- regular chow food
Group B- natural fish oil rich in DHA (10 mg) mixed into regular food
C- Caviar DNA Extract (LD-1227) 10 mg given orally with their regular diet

Group A demonstrated neuron cell degeneration  in CA1, CA2, Ca4 and also in Dg of hippocampus compared to the control (healthy) group. Nerve cell degeneration was observed in almost all 6 layers of the hippocampus. It is evident that in Group B (DHA )and Group C (Caviar DNA Extract), the number of degenerating cell bodies were significantly reduced and to a comparable extent. Cell bodies of all six layers of the hippocampus demonstrated normal neuronal morphology.

The Benefit of Caviarlieri on Brain Oxidative Stress


Results stress marker:

Corticosterone activity was significantly increased (156.6 µg/100ml) in muriels after applying the stress regimen. Corticosterone level almost doubled in stressed animals and Caviar Extract (LD-1227) treatment and DHA brought about a comparable partial improvement in stress levels (p<0.01 vs stressed animals).

Ascorbic acid content in the brain tissue, which can be a preliminary marker of stress, decreased in stress treated animals (1.4 mg/100ml) as compared to healthy control (2.4 mg/100 ml of tissue; p < 0.01). After treatment with Caviar Extract (LD-1227), an increase in ascorbic acid content was observed and also reached a statistic significance level (p < 0.01). The values shown are almost close to the healthy control group.

Accordingly, the SOD activity was significantly decreased by over 33% in stressed animals as compared to control (p < 0.005), and it was restored only in the C group who were treated with Caviar Extract (p<0.05 vs B group, p<0.001 vs A group).

Catalase level in the experimental groups demonstrated a significant change as compared to control with a decrease in the A group by 40% and was restored only in C group muriels treated with Caviar Extract (Ld-1227) (p<0.05 vs B group, p<0.01 vs A group).

The spontaneous MDA activity was the highest in the stress group (2.9 nmoles/ml) when compared to respective concentration of MDA in muriels treated with either supplement in which the content normalized (A group vs healthy control: p <0.001) (Table 2).

Conclusion

Both supplements stimulated neurogenesis in vitro and neurons marker in particular but the markers such as og oligodendrocytes and glia increased only in those who took the Caviar Extract (LD-1227)-enriched medium. Taken together these data suggest that Caviar Extract (LD-1227) is able to significantly protect brain structure redox system at a higher degree than DHA.

Other Evidence-Based Benefits of Caviarlieri

Improves Mental Health & Sleep Quality

Clinical studies have shown that marine peptides in Caviarlieri can effectively improve your mental health, mental fatigue and improve the quality of your sleep.

Significant Reduction in Inflammation

Caviarlieri is scientifically proven to have very strong anti-inflammatory properties. Formulated with the finest Caviar Cellular Extracts, marine peptides and highly polymerized collagen, it can help reduce chronic inflammation.

Significant Increase in Cellular Energy

Caviarlieri Swiss Caviar Cellular Therapy Supplement provides effective and essential nutrition at the cellular level, accelerating protein synthesis, stimulating cellular repair and renewal against damaged cells, providing you more energy, endurance and stamina.

“I always aspire to lead an active lifestyle regardless of my age but it can be very challenging to sustain energy levels as we age chronologically. My doctor recommended me Caviarlieri and it has transformed my life. Not only do I experience a surge in energy levels, physical stamina, my sleep quality has improved significantly as well.

With the pandemic, many of my friends feel a little stressed, anxious and depressed. Not for me. Caviarlieri elevates my mood and I feel great. It also helps me in my mental focus and concentration. Without a doubt, I am a fan.”

“Caviarlieri works on multiple levels. Most patients reported improved energy levels, better sleep quality, enhanced skin complexion in the first few weeks of taking Caviarlieri. In the sixth week, many of my patients also reported significant reduction in joint pain and inflammation, mood elevation, increased sexual desire and libido, just to name a few.”

“Since I started using Caviarlieri, I noticed a huge improvement in my Stamina and Endurance. Overall, my muscle fatigue and soreness were reduced significantly. My sleep quality has improved tremendously, and my mood is also elevated. I can train harder and I am definitely more focused.”

“Regardless of their age, all of the patients show improvement in energy levels, enhancement in collagen levels, significant reduction in inflammation. This means that Caviarlieri can trigger epigenetics changes, which is really revolutionary and ground breaking. It was a Eureka moment for me as a research scientist to discover a product  which can benefit patients at a molecular, cellular and genetic level, unheard of any other food supplement.”

“One of my 59 year old patient had a lump on her right breast and the doctor recommended to have it removed. After taking Caviarlieri for 3 months, the lump was gone. Another 50 year old patient has joint pain on the knee and after taking Caviarlieri for 2 weeks , the pain was significantly reduced and the swelling and inflammation reduced as well.

Caviarlieri also helps in sexual satisfaction as told by my 60 year old patient. She mentioned that her vaginal lubrication has improved after taking Caviarlieri for few months.”

“As an aesthetic doctor and dermatologist, I really appreciate the outstanding benefits of Caviarlieri. Not only does it improve my skin complexion, I find significant increase in my energy levels and enhancement of sexual desire only weeks after taking the Caviar Supplement.

Based on the scientific studies, it is also evident that Caviarlieri can benefit at a cellular and molecular level, which is unbelievable. It also helps improve my quality of sleep, which is few and precious due to my heavy work schedule.

I have taken this product for more than 6 months and I know I will continue with this product for vitality, youth and beauty.”

“With Caviarlieri, I feel like a young man bursting with energy and vitality even though I am 83 years old. Not only do I feel energised and optimistic, this caviar supplement also helped in my recovery from my quintuple bypass, hip replacement and shoulder replacement surgeries. In spite of my hectic work schedule, my mental focus and concentration are excellent. Furthermore, my students and colleagues always ask me how I manage to be as active as a 38 year old and what the secret to my high energy level is! I know it is because of Caviarlieri.”

“As a Professor in Obstetrics and Gynaecology and a medical expert in IVF discipline, I am sceptical about the benefits and claims of any health supplement unless it is backed by empirical evidence. When I first came to know Caviarlieri, I was impressed by the list of scientific studies published in peer reviewed journals , demonstrating that this caviar supplement is backed by science. I found the evidence in support of Caviarlieri’s use in many therapeutic indications extremely compelling.When I finally got to try Caviarlieri, I was astounded that even though I am over 65 years of age, I feel that I am able to function and work like I did 30 years ago. My mental focus and stamina have increased incredibly and I am able to focus and concentrate on many complex issues simultaneously from early morning to late at night, much to the surprise of my fellow colleagues.I am a living testament to the amazing benefits of this product.”

“Life expectancy is increasing but we need to get it in good health.We want to be optimistic, to maintain our physical appearance, our mechanical functionality and our brain even as we age. Caviarlieri is based on Science. It is proven to help increase energy levels, reduce inflammation for joint pain and increase collagen for our skin and tissues. It’s a wonderful product for depression, brain degeneration and even fibromyalgia. This is the secret of life, of aging and preventing aging. The best thing I can tell you is I am taking it for myself.”

“I am Isabel Bastos,Hhead Therapist of Le Grand Bellevue Gstaad.

I have been very lucky to be the brand ambassador of Caviarlieri.

Why? Because I started to take it and I love the results that I had in my body because im a spa therapist and we lose a lot of energy. My skin really looks better. I am 52.

My bodies issues, they are really getting really really better and the thing that I like more is that my guests had the chance to take it for 3 months and they didn’t want to stop it. Because each of them, in a different way feels the results. In the skin, in the body, a lot of people at this moment, like we know are suffering from COVID and might be feeling a little bit sick but after taking this, they feel more energized, they sleep better and even to their normal life, the things are really getting better. Please try it. Just give it chance, don’t doubt like me because we have thousands of products like this in the world, but this is really special.”

“This is especially important in the most delicate times of a woman, so I don’t lose energy or feel tired. I am extremely happy to say that Caviarlieri is an exceptional supplement, important to my life and will be continuing to take it.”

“I am chief of Internal Medicine and Anti-Aging at the Metropolitan Hospital and the owner of Orthobiotiki Anti-Aging Clinic. The last 7 years I was Vice President of ESSAM, European Society of Anti-Aging Medicine.

The Swiss Cell Treatment, Caviarlieri renews old cells, reduces and controls inflammation and other medical conditions which are age-related.

As an internist, I have discovered that Caviarlieri helps reduce inflammation of the joints significantly in addition to a reduction in the pain. It also helps to lower glucose levels which therefore benefit the diabetics and the non-diabetics. In my opinion Caviarlieri fulfils all the 5 criteria that defines an Anti-Aging product.”

“I am an outdoor sports enthusiast who enjoys travelling, diving, swimming, skiing, fitness and hiking. In late 2017 , while doing my sports activities, I injured my knees and was diagnosed with grade 3 Chondropathy. This is a disease of the cartilage and is caused by inflammation and damage to the knee cartilage. The pain can be difficult at times but I tried to manage. The doctors gave me the usual advice .They told me to avoid the overuse of my knees and to go for physiotherapy treatments.
This potentially meant that I have to avoid engaging in some sports activities indefinitely, which was devastating for me. Dr. Brigitte Bollinger, a reputable dermatologist from Bad Ragaz Medical Center then introduced me to Caviarlieri. She told me that this caviar supplement is able to provide essential nutrition at the cellular level thereby stimulating cellular repair and renewal against the damaged cells in my knees. She assured me that Caviarlieri is backed by science and it is a supplement and not a drug. The results have been phenomenal. After 4 months of taking Caviarlieri, I was amazed at my recovery. I am now able to resume sports and outdoor activities like before. Most importantly I am so thrilled that I am able to ski again and my life has returned back to normalcy.”

“I am a medical doctor who has worked about 60 to 80 hours a week for the past 20 years. I was tired all the time and my sleep was not restful. I started to feel more energy within the first two weeks of taking Caviarlieri. I also gave it to my husband and noticed that his memory has improved significantly. We both sleep better and wake up with more energy. It is expensive but my health is invaluable and I am worth it.”

“The benefits of taking Caviarlieri for me have been significant. Prior to taking them I had been diagnosed with Rheumatoid Arthritis but the symptoms have been 90% improved in the last year.  My asthma symptoms have also improved drastically by 80% and most of the time I have no need for an inhaler.”

“Caviarlieri helps boost my strength and stamina.

I have been taking Caviarlieri for almost 1 year and the benefits I experience from this caviar supplement are extraordinary. The product was recommended to me by Dr. Sotiris Nikolopoulos and Dr. Michael Papacharalampous, both world renowned doctors in Athens.

I was amazed that Caviarlieri – Swiss Caviar Cell Therapy supplement has helped increase my cellular energy significantly , improve my sleep quality and enhance my physical stamina and endurance. Caviarlieri has definitely helped enhance my performance at the Tokyo Olympics 2021.

Henceforth, I will continue to take this supplement as it is a product not only backed by science with peer-reviewed studies and it is also listed in the Cologne List® which is committed to “clean sports” and promotes safety through tested products.”

“I have been taking Caviarlieri for more than 1 year and the benefits I experienced are phenomenal and outstanding. The potency of the product is undeniable, I am invigorated to exercise and my mental concentration has improved significantly. At 86, I am full of life and people are amazed how I am able to walk briskly without joint pain and I can even surpass the work schedule of my employees and my daughters who are responsible for the management of the hospitals. Many people also commented on my skin complexion and glow.

Caviarlieri also helps to regulate my blood sugar levels , reduce
inflammation and is very effective in preventing brain degeneration. I look forward to taking this Caviar Supplement every single morning.”