Helps Control High Blood Pressure/ Hypertension

Helps Control High Blood Pressure/ Hypertension

High blood pressure or hypertension is severely injurious to our health because it exerts undue pressure on the heart to work harder than normal in order to pump blood to our heart and into the other organs of our body. After a period of time this will cause the hardening of our arteries, a condition known as atherosclerosis. Persistent high blood pressure if left untreated can increase your risk of a number of serious and potentially life-threatening health conditions, such as heart disease, heart failure, heart attacks, strokes, kidney disease etc.

Nearly half of the adults in the United States (108 million, or 45% of the population) have hypertension. Hypertension is defined as a condition when your systolic blood pressure is above 130 mmHg or your diastolic blood pressure is below 80 mmHg. It is estimated that only about 1 in 4 adults (24%) with hypertension have their condition under control.

Most people who have high blood pressure do not display symptoms which gives an early warning of their condition.

Why Caviarlieri

Caviarlieri is scientifically proven to help reduce the inflammatory infiltration of the intima, which is the innermost part of a blood vessel. Arteries are the blood vessels that deliver oxygen-rich blood from the heart to the tissues of the body. High blood pressure patients usually have “thickened intima” or hardening of the blood vessels.

A study on Caviarlieri published in Europe PMC with the title “Protective Effect of a Fish Egg Homogenate Marine Compound on Arterial Ultrastructure in Spontaneous Hypertensive Rats” shows that the “thickened intima/ blood vessels” in spontaneous hypertensive rats were significantly reduced when treated with Caviar DNA Extracts- LD 1227. This will potentially reduce the risks of cardiovascular diseases.

The same study also demonstrates significant reduction in endothelial damage and dysfunction in spontaneous hypertensive rats treated Caviar DNA Extracts- LD 1227. In endothelial dysfunction, the vasodilation is impaired, and the arteries begin to lack the ability to dilate properly. This dysfunction can be a significant predictor of coronary artery disease and atherosclerosis, a chronic disease which can cause a stroke or heart attack.

Therefore, the results of the study suggests that Caviarlieri has “arterial protective properties” and may potentially help prevent the onset and delay the progression of cardiovascular diseases.

Protective Effect of a Fish Egg Homogenate Marine Compound on Arterial Ultrastructure in Spontaneous Hypertensive Rats

1. Published in Peer Reviewed Journal – Rejuvenation Research Volume 17 Number 2, April 2014

Nicola Zerbinati,1 Francesco Marotta,2 Ravinder Nagpal,3,4 Birbal Singh,5 Dheeraj Mohania,6 Michele Milazzo,7 Angelo Italia,7 Claudio Tomella,2 and Roberto Catanzaro7

It has been reported that lipid peroxidation may be partly responsible for the detrimental effects of changes in arterial structure caused by hypertension. This study  assessed the effect of a sturgeon eggs–based nutraceutical Caviar Cellular DNA Extract (LD-1227 – Caviarlieri) as compared to EPA/DHA on the ultrastructure of spontaneously hypertensive rat (SHR) aortas. The aorta is the main and largest artery in the human body. Sixty SHR were randomly divided into three groups that were fed (1) rat chow, (2) rat chow plus 10 mg of EPA/DHA, or (3) rat chow plus 10 mg of LD-1227, for 18 weeks. Afterward, the aortas of these rats were used for blind measurements of the thickened intima area and examination by electron microscopy. Control SHR showed an expanded subendothelial space and leukocyte infiltration of the intima that were reduced in LD-1227–fed rats ( p < 0.05) and less in EPA/DHA group.

Transmission electron microscopy showed endothelial alteration with severe subcellular injury and, unlike the EPA/DHA-group, LD-1227–treated rats displayed a significant reduction in endothelial alteration with severe subcellular injury ( p < 0.05). These data suggest that LD-1227 has stronger arterial protective properties and deserves further investigation for use for  a preventive medicine strategy.

Figure.1 Light microscopy and electron microscopy analysis of arterial structure in spontaneously hypertensive rats (SHR): Effect of LD-1227 (Thickened Intima)

It is evident the “thickened intima/blood vessels” were significantly reduced in rats that were treated with Caviar DNA Extracts- LD 1227.

Measurements:  (4110 µm² vs. 5530 µm² , p = 0.05) for rats treated with 10 mg of DHA. Caviar DNA Extract is more effective in reducing hypertension than DHA.

Thickened Intima of rats that are not treated with DHA or Caviar DNA Extracts.

Measurement : 7147 µm²

Thickened Intima of rats that are treated with DHA showed reduction with DHA even though it is not as effective Caviar DNA Extract.

Measurement :5530 µm² vs 7147 µm² non treated rats p = 0.05)

Figure. 2 Transmission electron microscopy analysis of arterial structure in spontaneously hypertensive rats (SHR): Effect of LD-1227

It is evident that the rats treated with Caviar DNA Extracts- LD 1227 displayed a significant reduction in structural alteration of endothelial cells with severe subcellular injury (atypical mitochondria of smooth muscle cells, such as swollen and vacuolated mitochondria, and several vacuoles and electron-lucent chromatin).

SHR showed an increase in the density and frequency of occurrences of cytoplasmic vacuoles and cytoplasmic processes of endothelial cells, with longer and more slender cytoplasmic processes.

Unlike the Caviar DNA Extract treated rats, in the EPA/DHA-group of rats , there is no apparent reduction of structural alteration of endothelial cells with severe subcellular injury.

Therefore, DHA is less effective than Caviar DNA Extract .

Conclusive Summary

Hypertension represents a main risk factor of cardiovascular diseases which is linked with endothelial dysfunction. Structural abnormalities of endothelium in vessels observed in hypertensive animals indicated their likely contribution to the development or maintenance of high blood pressure. Hypertension is associated with structural changes in blood vessels known as ‘‘vascular remodelling’’ that include dynamic structural changes involving cell growth, migration, phenotypic changes, and extracellular matrix synthesis and degradation. Effects of LD-1227 on the expression of angiotensin-converting enzyme 2, mitogen-activated protein kinase (MAPK) signalling, and peroxisome proliferator activated receptor-c in aortas of SHR are evident, and preliminary in-house data show a significant beneficial modulation exerted by this marine nutraceutical.

In conclusion, these preliminary data suggest that Caviar DNA Extract, LD-1227 has stronger arterial protective properties than EPA/DHA and further studies are being done to evaluate Caviarlieri for a preventive cardiovascular protective medical strategy against hypertension.

Other Evidence-Based Benefits of Caviarlieri

Substantial Reduction in Joint Pain

Caviarlieri has strong anti-inflammatory properties that can help alleviate and reduce chronic joint pain significantly. Unlike painkillers or opioids which have adverse side effects, Caviarlieri is an excellent nutritional supplement which has no side effects and is a palliative for chronic pain management.

Improves Sexual Performance

Oxidative stress is a common pathology seen in approximately half of all infertile men. Caviarlieri can help reduce oxidative stress and cellular damage to stimulate increase in sperm count and sperm viability.

Improves Mental Health & Sleep Quality

Clinical studies have shown that marine peptides in Caviarlieri can effectively improve your mental health, mental fatigue and improve the quality of your sleep.

“The benefits of taking Caviarlieri for me have been significant. Prior to taking them I had been diagnosed with Rheumatoid Arthritis but the symptoms have been 90% improved in the last year.  My asthma symptoms have also improved drastically by 80% and most of the time I have no need for an inhaler.”

“I am a medical doctor who has worked about 60 to 80 hours a week for the past 20 years. I was tired all the time and my sleep was not restful. I started to feel more energy within the first two weeks of taking Caviarlieri. I also gave it to my husband and noticed that his memory has improved significantly. We both sleep better and wake up with more energy. It is expensive but my health is invaluable and I am worth it.”

“I am an outdoor sports enthusiast who enjoys travelling, diving, swimming, skiing, fitness and hiking. In late 2017 , while doing my sports activities, I injured my knees and was diagnosed with grade 3 Chondropathy. This is a disease of the cartilage and is caused by inflammation and damage to the knee cartilage. The pain can be difficult at times but I tried to manage. The doctors gave me the usual advice .They told me to avoid the overuse of my knees and to go for physiotherapy treatments.
This potentially meant that I have to avoid engaging in some sports activities indefinitely, which was devastating for me. Dr. Brigitte Bollinger, a reputable dermatologist from Bad Ragaz Medical Center then introduced me to Caviarlieri. She told me that this caviar supplement is able to provide essential nutrition at the cellular level thereby stimulating cellular repair and renewal against the damaged cells in my knees. She assured me that Caviarlieri is backed by science and it is a supplement and not a drug. The results have been phenomenal. After 4 months of taking Caviarlieri, I was amazed at my recovery. I am now able to resume sports and outdoor activities like before. Most importantly I am so thrilled that I am able to ski again and my life has returned back to normalcy.”

“I am chief of Internal Medicine and Anti-Aging at the Metropolitan Hospital and the owner of Orthobiotiki Anti-Aging Clinic. The last 7 years I was Vice President of ESSAM, European Society of Anti-Aging Medicine.

The Swiss Cell Treatment, Caviarlieri renews old cells, reduces and controls inflammation and other medical conditions which are age-related.

As an internist, I have discovered that Caviarlieri helps reduce inflammation of the joints significantly in addition to a reduction in the pain. It also helps to lower glucose levels which therefore benefit the diabetics and the non-diabetics. In my opinion Caviarlieri fulfils all the 5 criteria that defines an Anti-Aging product.”

“This is especially important in the most delicate times of a woman, so I don’t lose energy or feel tired. I am extremely happy to say that Caviarlieri is an exceptional supplement, important to my life and will be continuing to take it.”
“Life expectancy is increasing but we need to get it in good health.We want to be optimistic, to maintain our physical appearance, our mechanical functionality and our brain even as we age. Caviarlieri is based on Science. It is proven to help increase energy levels, reduce inflammation for joint pain and increase collagen for our skin and tissues. It’s a wonderful product for depression, brain degeneration and even fibromyalgia. This is the secret of life, of aging and preventing aging. The best thing I can tell you is I am taking it for myself.”
“Caviarlieri works on multiple levels. Most patients reported improved energy levels, better sleep quality, enhanced skin complexion in the first few weeks of taking Caviarlieri. In the sixth week, many of my patients also reported significant reduction in joint pain and inflammation, mood elevation, increased sexual desire and libido, just to name a few.”

“As a Professor in Obstetrics and Gynaecology and a medical expert in IVF discipline, I am sceptical about the benefits and claims of any health supplement unless it is backed by empirical evidence. When I first came to know Caviarlieri, I was impressed by the list of scientific studies published in peer reviewed journals , demonstrating that this caviar supplement is backed by science. I found the evidence in support of Caviarlieri’s use in many therapeutic indications extremely compelling.When I finally got to try Caviarlieri, I was astounded that even though I am over 65 years of age, I feel that I am able to function and work like I did 30 years ago. My mental focus and stamina have increased incredibly and I am able to focus and concentrate on many complex issues simultaneously from early morning to late at night, much to the surprise of my fellow colleagues.I am a living testament to the amazing benefits of this product.”

“With Caviarlieri, I feel like a young man bursting with energy and vitality even though I am 83 years old. Not only do I feel energised and optimistic, this caviar supplement also helped in my recovery from my quintuple bypass, hip replacement and shoulder replacement surgeries. In spite of my hectic work schedule, my mental focus and concentration are excellent. Furthermore, my students and colleagues always ask me how I manage to be as active as a 38 year old and what the secret to my high energy level is! I know it is because of Caviarlieri.”

“As an aesthetic doctor and dermatologist, I really appreciate the outstanding benefits of Caviarlieri. Not only does it improve my skin complexion, I find significant increase in my energy levels and enhancement of sexual desire only weeks after taking the Caviar Supplement.

Based on the scientific studies, it is also evident that Caviarlieri can benefit at a cellular and molecular level, which is unbelievable. It also helps improve my quality of sleep, which is few and precious due to my heavy work schedule.

I have taken this product for more than 6 months and I know I will continue with this product for vitality, youth and beauty.”

“One of my 59 year old patient had a lump on her right breast and the doctor recommended to have it removed. After taking Caviarlieri for 3 months, the lump was gone. Another 50 year old patient has joint pain on the knee and after taking Caviarlieri for 2 weeks , the pain was significantly reduced and the swelling and inflammation reduced as well.

Caviarlieri also helps in sexual satisfaction as told by my 60 year old patient. She mentioned that her vaginal lubrication has improved after taking Caviarlieri for few months.”

“Regardless of their age, all of the patients show improvement in energy levels, enhancement in collagen levels, significant reduction in inflammation. This means that Caviarlieri can trigger epigenetics changes, which is really revolutionary and ground breaking. It was a Eureka moment for me as a research scientist to discover a product  which can benefit patients at a molecular, cellular and genetic level, unheard of any other food supplement.”

“Since I started using Caviarlieri, I noticed a huge improvement in my Stamina and Endurance. Overall, my muscle fatigue and soreness were reduced significantly. My sleep quality has improved tremendously, and my mood is also elevated. I can train harder and I am definitely more focused.”

“I have been taking Caviarlieri for more than 1 year and the benefits I experienced are phenomenal and outstanding. The potency of the product is undeniable, I am invigorated to exercise and my mental concentration has improved significantly. At 86, I am full of life and people are amazed how I am able to walk briskly without joint pain and I can even surpass the work schedule of my employees and my daughters who are responsible for the management of the hospitals. Many people also commented on my skin complexion and glow.

Caviarlieri also helps to regulate my blood sugar levels , reduce
inflammation and is very effective in preventing brain degeneration. I look forward to taking this Caviar Supplement every single morning.”