Substantial Reduction
in Joint Pain

Substantial Reduction
in Joint Pain

Musculoskeletal pain, particularly joint and back pain, is the most common type of chronic pain. The most common cause of joint pain is related to arthritis, of which there are numerous types. Patients routinely seek medical attention for joint pain, and it is one of the leading causes of disability.

Joint problems and diseases worldwide today ranks fifth amongst all forms of disability, affecting 10 percent of the world’s population over the age of 60. It is also estimated that degenerative joint disorders will affect 130 million individuals worldwide by the year 2050.

It is inevitable that the majority of people suffering from joint pain are dependent on painkillers and drugs like NASIDs (nonsteroidal anti-inflammatory drugs). This is a very serious problem as many of those drugs and painkillers have adverse side effects. Long-term use of certain NSAIDs can lead to side effects including stomach problems, kidney problems, high blood pressure, fluid retention, and other allergic reactions.

Opioids (also known as narcotics) are also prescribed to treat moderate to severe pain. However with long-term use, they too have other side effects such as hormonal dysfunction including reduced fertility and libido, immunosuppression, testosterone depletion, and abnormal pain sensitivity.

NASIDs and Opioids also become less effective after some time.

Why Caviarlieri


Caviarlieri is a Swiss Caviar Food Supplement formulated with the finest Caviar Cellular Extracts and marine peptides and highly polymerized collagen which have strong anti-inflammatory properties. It can help to alleviate and reduce chronic joint pain significantly.

Unlike painkillers or opioids which have adverse side effects, Caviarlieri is an excellent nutritional supplement which has no side effects and is a palliative for chronic pain management. Scientific studies of Caviarlieri published in peer reviewed journals have demonstrated that its primary bio active ingredient, Caviar DNA Extract is more effective than DHA and its positive results become more significant over time (18 weeks).

Empirical randomised double-blind placebo studies of the key ingredients of Caviarlieri also show outstanding results for knee osteoarthritis and back pain. In a published scientific study on Caviarlieri, it was reported that Caviarlieri can also reduce the Tumour Necrosis Factor Alpha which is an important inflammatory biomarker for arthritis and fibromyalgia. There are also several ongoing studies which indicate that Caviarlieri triggers the epigenetic mechanisms of the cells to activate gene expression for inflammation reduction.

Effective Treatment for Osteoarthritis with No Side Effects


Osteoarthritis is the most common form of arthritis, affecting millions of people worldwide. It occurs when the protective cartilage that cushions the ends of your bones wears down over time. It is a progressive chronic disease that can lead to impaired joint function and will result in excruciating pain and disability.

Published in Peer Reviewed Journal – Acta Bio Medical / Official Journal of the Society of Medicine and Natural Sciences of Parma Vol 84-N1/2013

Testing a novel bioactive marine nutraceutical (Caviarlieri) on Osteoarthritis patients

The primary objective of the study was to test the effectiveness of the Caviar bioactive compound versus a common nutraceutical intervention like GC (glucosamine/chondroitin sulphate) in knee osteoarthritis patients. The patient population involved in the study consisted of 60 subjects who had a recent diagnosis of knee osteoarthritis of mild-moderate severity. The patients were randomized in two groups in a double-blind study comparing Caviar Extract LD-1227 (group A) versus a mixture of glucosamine (500 mg), chondroitin sulphate (400 mg) (group B). Patients were allowed their established painkillers on demand. At 4, 9 and 18 weeks patients were evaluated based on various validated pain score systems like VAS score which assesses pain at rest, and during physical exercise, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scale and KOOS scale.

Figure 1. Pain at Rest (VAS core) through week 18: Effect of Caviar DNA Extract versus GC Treatment

It is evident from the above figure 1 that after 4 weeks, patients treated with Caviar DNA extract (LD1227) showed a decline in VAS Score (p<0.05) which means that the pain (at rest) for these patients is significantly lower those treated with Glucosamine Chondroitin (GC).

Note: VAS Score is a 0-100mm Visual Analog Scale Score system which assesses pain during the most painful knee movement.

Figure 2. Pain During Physical Activity (VAS Score) through week 18: Effect of Caviar DNA Extract versus GC Treatment

This graph shows the assessment of pain during routine physical activity and it is obvious that both treatments yielded comparable improvement at the 4th week. However, from week 9th till week 18th, patients treated with Caviar DNA extract (LD-1227) showed a significantly lower pain intensity as compared to those on GC.

Figure 3. Koos Scale Evaluation – Reduction of Pain for Knee Osteoarthritis Subjects using Caviar DNA and GC Treatment

This graph shows that once again that Caviar DNA extract (LD-1227) can help reduction in pain and is a outstanding option for pain management in the long term.

Note: KOOS (Knee disability and Osteoarthritis) score system is divided into 5 segments namely pain symptoms, function in daily living, function in recreation, other symptoms and quality of life.

Figure 4. Koos Scale Evaluation – Function in Recreation for Knee Osteoarthritis Subjects using Caviar DNA and GC Treatment

Patients treated with Caviar DNA extract (LD-1227) have excellent sustainable improvements in recreational functionality from baseline to week 18 as compared to GC.

Figure 5. Womac Asessment of Patients with Knee Osteoarthrtis Treated with Caviar DNA Extract Versus GC – Level of Pain

This graph confirmed and reinforced the results and outcomes measured using VAS Score and KOOs score system in terms of significant pain reduction for Knee Osteoarthritis patients administered with Caviar DNA extract (LD-1227) as compared to GC.

Note: WOMAC (Western Ontario and McMaster Universities Osteoarthritis Index)

Figure 6. Womac Assessment of Patients with Knee Osteoarthritis Treated with Caviar DNA Extract Versus GC – Stiffness

Graph demonstrates that patients administered with Caviar DNA extract (LD-1227) have reported significant reduction in the stiffness of their joints from baseline to 18th week compared to GC.

Biochemical Monitoring of Inflammatory Markers in Patients with Knee Osteoarthritis Treated with Caviar DNA (LD-1227) and GC

Biochemistry Analysis – Blood tests


Patients in the two groups were tested for inflammatory markers like Tumour Necrosis Factor Alpha, C Reactive Protein, Interleukin 6 etc, cytokines during the 18 weeks study period after taking the Caviar DNA extract (LD-1227) versus those taking GC.

Table 7 demonstrates that patients administered with Caviar DNA extract (LD-1227) have demonstrated significantly Lower Inflammation over time as compared to GC. This implies that Caviarlieri can not only help to reduce joint pain and chronic inflammation over time.

Conclusive Summary


Most doctors usually prescribe Glucosamine Chondroitin for osteoarthritis patients suffering from joint pain. However, it is evident from the above studies that Caviarlieri is far more potent and effective for the long-term reduction of joint pain as compared to the widely prescribed glucosamine chondroitin. In addition, Caviarlieri’s strong anti-inflammatory properties will also reduce disability, enhance recovery and functional physical mobility significantly.

Empirical Randomised Double Blind Placebo Clinical Studies on Key Ingredients of Caviarlieri on Osteoarthritis

Effect of Marine Peptides in Caviarlieri on Osteoarthritis after a month

This graph explains how patients who were administered with marine peptides in Caviarlieri after a month have all reported significant improvements in their physical performance. 21% of the patients also reported complete relief from pain.

Effect of Marine Peptides in Caviarlieri on Osteoarthritis after 24 days

This graph explains the reduction of pain between treatment with marine peptides in Caviarlieri versus Diclofenac. After 42 days, patients who were treated with Caviar & Marine Cellular DNA reported a 39% reduction in pain.

Cartilage Repair and Growth

Effectiveness of Marine Peptides in Caviarlieri in reducing intra-cellular collagenase (growing chondrocyte/
cartilage cells) – anti-osteoarthritis basic effect

This graphs shows that by significantly inhibiting or reducing intra-cellular collagenase, Marine Peptides in Caviarlieri helps facilitate the growth of chondrocytes (cartilage cells), thereby demonstrating a strong anti-osteoarthritis effect.

Note: When chondrocytes cells break, it becomes easier for bacteria or inflammatory elements to enter our system. Therefore, is it essential that we grow chondrocytes and also inhibit the breaking down of extra cellular matrix – important for fighting or battling osteoarthritis.



It is evident from both the Caviarlieri scientific studies and empirical studies on the key ingredients of Caviarlieri, that there is consistency in terms of sustainable results and outcomes in significantly reducing joint pain, improving functional mobility and the quality of life for Osteoarthritis patients without adverse side effects over time.

Effective Treatment for Rheumatoid Arthritis

Rheumatoid Arthritis is an autoimmune condition that brings about inflammation in your joints which leads to pain, swelling and stiffness in joints. This condition causes the immune system to attack healthy body tissues. Rheumatoid Arthritis is commonly known to affect the knees, feet and hands and there is no cure. However, the damage and pain can be reduced or managed with early and continuous treatment.

The graph above shows that marine peptides in Caviarlieri have a beneficial effect on swollen joints.

Other Evidence-Based Benefits of Caviarlieri

Supports Bone Health

Marine peptides inherent in Caviarlieri have properties which are beneficial for bone health and support. The peptides help increase the organic component of bones including the bone microarchitecture. It helps to improve bone formation and bone density and also prevents bone loss.

Significant Reduction in Inflammation

Caviarlieri is scientifically proven to have very strong anti-inflammatory properties. Formulated with the finest Caviar Cellular Extracts, marine peptides and highly polymerized collagen, it can help reduce chronic inflammation.

Significant Increase in Cellular Energy

Caviarlieri Swiss Caviar Cellular Therapy Supplement provides effective and essential nutrition at the cellular level, accelerating protein synthesis, stimulating cellular repair and renewal against damaged cells, providing you more energy, endurance and stamina.

“I am a 47 year old active woman. I initially took Caviarlieri for 3 consecutive months and I noticed an improvement in my mood, energy levels and menstrual cycle. It’s when I decided to stop for the summer time when I noticed a huge difference.  My cycle went completely off track, I had severe cramps and a lot of mood swings.  Since I got back on Caviarlieri all these symptoms disappeared, I have regained my energy and good moods.  

After seeing its positive effects on me I introduced it to my 67 year old husband who experienced similar positive effects.  On top of extra energy and good mood, he also noticed an increase in his libido and a decrease in his blood sugar daily readings without any other change in his lifestyle.  There is no turning back for us anymore.”
“Caviarlieri works on multiple levels. Most patients reported improved energy levels, better sleep quality, enhanced skin complexion in the first few weeks of taking Caviarlieri. In the sixth week, many of my patients also reported significant reduction in joint pain and inflammation, mood elevation, increased sexual desire and libido, just to name a few.”

“Since I started using Caviarlieri, I noticed a huge improvement in my Stamina and Endurance. Overall, my muscle fatigue and soreness were reduced significantly. My sleep quality has improved tremendously, and my mood is also elevated. I can train harder and I am definitely more focused.”

“Regardless of their age, all of the patients show improvement in energy levels, enhancement in collagen levels, significant reduction in inflammation. This means that Caviarlieri can trigger epigenetics changes, which is really revolutionary and ground breaking. It was a Eureka moment for me as a research scientist to discover a product  which can benefit patients at a molecular, cellular and genetic level, unheard of any other food supplement.”

“One of my 59 year old patient had a lump on her right breast and the doctor recommended to have it removed. After taking Caviarlieri for 3 months, the lump was gone. Another 50 year old patient has joint pain on the knee and after taking Caviarlieri for 2 weeks , the pain was significantly reduced and the swelling and inflammation reduced as well.

Caviarlieri also helps in sexual satisfaction as told by my 60 year old patient. She mentioned that her vaginal lubrication has improved after taking Caviarlieri for few months.”

“As an aesthetic doctor and dermatologist, I really appreciate the outstanding benefits of Caviarlieri. Not only does it improve my skin complexion, I find significant increase in my energy levels and enhancement of sexual desire only weeks after taking the Caviar Supplement.

Based on the scientific studies, it is also evident that Caviarlieri can benefit at a cellular and molecular level, which is unbelievable. It also helps improve my quality of sleep, which is few and precious due to my heavy work schedule.

I have taken this product for more than 6 months and I know I will continue with this product for vitality, youth and beauty.”

“With Caviarlieri, I feel like a young man bursting with energy and vitality even though I am 83 years old. Not only do I feel energised and optimistic, this caviar supplement also helped in my recovery from my quintuple bypass, hip replacement and shoulder replacement surgeries. In spite of my hectic work schedule, my mental focus and concentration are excellent. Furthermore, my students and colleagues always ask me how I manage to be as active as a 38 year old and what the secret to my high energy level is! I know it is because of Caviarlieri.”

“As a Professor in Obstetrics and Gynaecology and a medical expert in IVF discipline, I am sceptical about the benefits and claims of any health supplement unless it is backed by empirical evidence. When I first came to know Caviarlieri, I was impressed by the list of scientific studies published in peer reviewed journals , demonstrating that this caviar supplement is backed by science. I found the evidence in support of Caviarlieri’s use in many therapeutic indications extremely compelling.When I finally got to try Caviarlieri, I was astounded that even though I am over 65 years of age, I feel that I am able to function and work like I did 30 years ago. My mental focus and stamina have increased incredibly and I am able to focus and concentrate on many complex issues simultaneously from early morning to late at night, much to the surprise of my fellow colleagues.I am a living testament to the amazing benefits of this product.”

“Life expectancy is increasing but we need to get it in good health.We want to be optimistic, to maintain our physical appearance, our mechanical functionality and our brain even as we age. Caviarlieri is based on Science. It is proven to help increase energy levels, reduce inflammation for joint pain and increase collagen for our skin and tissues. It’s a wonderful product for depression, brain degeneration and even fibromyalgia. This is the secret of life, of aging and preventing aging. The best thing I can tell you is I am taking it for myself.”

“I always aspire to lead an active lifestyle regardless of my age but it can be very challenging to sustain energy levels as we age chronologically. My doctor recommended me Caviarlieri and it has transformed my life. Not only do I experience a surge in energy levels, physical stamina, my sleep quality has improved significantly as well.

With the pandemic, many of my friends feel a little stressed, anxious and depressed. Not for me. Caviarlieri elevates my mood and I feel great. It also helps me in my mental focus and concentration. Without a doubt, I am a fan.”

“This is especially important in the most delicate times of a woman, so I don’t lose energy or feel tired. I am extremely happy to say that Caviarlieri is an exceptional supplement, important to my life and will be continuing to take it.”

“I am chief of Internal Medicine and Anti-Aging at the Metropolitan Hospital and the owner of Orthobiotiki Anti-Aging Clinic. The last 7 years I was Vice President of ESSAM, European Society of Anti-Aging Medicine.

The Swiss Cell Treatment, Caviarlieri renews old cells, reduces and controls inflammation and other medical conditions which are age-related.

As an internist, I have discovered that Caviarlieri helps reduce inflammation of the joints significantly in addition to a reduction in the pain. It also helps to lower glucose levels which therefore benefit the diabetics and the non-diabetics. In my opinion Caviarlieri fulfils all the 5 criteria that defines an Anti-Aging product.”

“I am an outdoor sports enthusiast who enjoys travelling, diving, swimming, skiing, fitness and hiking. In late 2017 , while doing my sports activities, I injured my knees and was diagnosed with grade 3 Chondropathy. This is a disease of the cartilage and is caused by inflammation and damage to the knee cartilage. The pain can be difficult at times but I tried to manage. The doctors gave me the usual advice .They told me to avoid the overuse of my knees and to go for physiotherapy treatments.
This potentially meant that I have to avoid engaging in some sports activities indefinitely, which was devastating for me. Dr. Brigitte Bollinger, a reputable dermatologist from Bad Ragaz Medical Center then introduced me to Caviarlieri. She told me that this caviar supplement is able to provide essential nutrition at the cellular level thereby stimulating cellular repair and renewal against the damaged cells in my knees. She assured me that Caviarlieri is backed by science and it is a supplement and not a drug. The results have been phenomenal. After 4 months of taking Caviarlieri, I was amazed at my recovery. I am now able to resume sports and outdoor activities like before. Most importantly I am so thrilled that I am able to ski again and my life has returned back to normalcy.”

“I am a medical doctor who has worked about 60 to 80 hours a week for the past 20 years. I was tired all the time and my sleep was not restful. I started to feel more energy within the first two weeks of taking Caviarlieri. I also gave it to my husband and noticed that his memory has improved significantly. We both sleep better and wake up with more energy. It is expensive but my health is invaluable and I am worth it.”

“The benefits of taking Caviarlieri for me have been significant. Prior to taking them I had been diagnosed with Rheumatoid Arthritis but the symptoms have been 90% improved in the last year.  My asthma symptoms have also improved drastically by 80% and most of the time I have no need for an inhaler.”

“Caviarlieri helps boost my strength and stamina.

I have been taking Caviarlieri for almost 1 year and the benefits I experience from this caviar supplement are extraordinary. The product was recommended to me by Dr. Sotiris Nikolopoulos and Dr. Michael Papacharalampous, both world renowned doctors in Athens.

I was amazed that Caviarlieri – Swiss Caviar Cell Therapy supplement has helped increase my cellular energy significantly , improve my sleep quality and enhance my physical stamina and endurance. Caviarlieri has definitely helped enhance my performance at the Tokyo Olympics 2021.

Henceforth, I will continue to take this supplement as it is a product not only backed by science with peer-reviewed studies and it is also listed in the Cologne List® which is committed to “clean sports” and promotes safety through tested products.”

“I am Isabel Bastos,Hhead Therapist of Le Grand Bellevue Gstaad.

I have been very lucky to be the brand ambassador of Caviarlieri.

Why? Because I started to take it and I love the results that I had in my body because im a spa therapist and we lose a lot of energy. My skin really looks better. I am 52.

My bodies issues, they are really getting really really better and the thing that I like more is that my guests had the chance to take it for 3 months and they didn’t want to stop it. Because each of them, in a different way feels the results. In the skin, in the body, a lot of people at this moment, like we know are suffering from COVID and might be feeling a little bit sick but after taking this, they feel more energized, they sleep better and even to their normal life, the things are really getting better. Please try it. Just give it chance, don’t doubt like me because we have thousands of products like this in the world, but this is really special.”

“I have been taking Caviarlieri for more than 1 year and the benefits I experienced are phenomenal and outstanding. The potency of the product is undeniable, I am invigorated to exercise and my mental concentration has improved significantly. At 86, I am full of life and people are amazed how I am able to walk briskly without joint pain and I can even surpass the work schedule of my employees and my daughters who are responsible for the management of the hospitals. Many people also commented on my skin complexion and glow.

Caviarlieri also helps to regulate my blood sugar levels , reduce
inflammation and is very effective in preventing brain degeneration. I look forward to taking this Caviar Supplement every single morning.”